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What is antibiotic resistance? 
When an antibiotic cannot effectively control or kill the growth of bacterial or microorganism is known as antibiotic resistance. In the other word, the bacteria are “resistant” and continue to grow or multiply in the presence of antibiotic.
Why do bacteria become resistant to antibiotics? 
Antibiotic resistance is a natural phenomenon. When an antibiotic is used, bacteria that can resist that antibiotic have a greater chance of survival than those that are “susceptible”. Some resistance occurs without human action where a bacteria can produce and use antibiotics against other bacteria, leading to a low-level of natural selection for resistance to antibiotics. But the current higher-levels of antibiotic-resistant bacteria are attributed to the overuse and abuse of antibiotics. For example, patient will take antibiotics unnecessarily to treat viral illnesses such as the common cold.
Consequences of bacteria resistance
The danger of antibiotic resistance is that treatable diseases, such as pneumonia and tuberculosis could become incurable. This would put a greater economic and emotional burden on individual, society and healthcare system.
Antibiotic resistance may results in increased human illness, suffering and death; increased cost and length of treatments, and increased side effects from the use of multiple and more powerful medications. 
Infections caused by antimicrobial-resistant organisms also may require more toxic therapy that can leading to more or serious of adverse outcomes. For example, the use of colistin for highly resistant Pseudomonas or Acinetobacter infections is associated with a high risk of renal dysfunction . Patients who infected with organisms those are resistant to all available antimicrobials often require surgical procedures to remove the site of infection. However, patients with infections that are not advisable or cannot undergo surgical will have high mortality rates. 
Prevention and control 
By pharmacy Department, Sri Kota Specialist Medical Centre